Environmental Toxic Substances -Neurotoxicity of Organotin Compounds-

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Neurotoxicity Induced by Environmental Low-molecular-weight Substances

The neurotoxicity of Parkinson’s disease (PD)-related tetrahydroisoquinolines (TIQs) and organotins is reviewed. PD is one of the most common neurodegenerative diseases among aged people and characteristized by the selective death of nigrostriatal dopaminergic neurons, but its pathological mechanism remains unknown. 1-Benzyl1,2,3,4-tetrahydroisoquinoline (1BnTIQ), an endogenous brain amine, was...

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Organotin Compounds and the Environment

Organotin compound that have at least one Sn-C bond have wide commercial applications as PVC stabilizer, antifouling agent in paint and as agrochemicals. The general formula for organotin compounds is R4SnX4 - n where R is normally alkyl or aryl groups and X=Cl-, OH-, CH3COO- . If n=3, the compound has the highest toxicity, for example Et3SnOAC has LD 50 4mg/Kg ( rats ) and this is the m...

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Developmental toxicity of organotin compounds in animals

*Correspondence: Xiao Huang, Institute of Cellular and Developmental Biology, College of Life Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China e-mail: [email protected]; Huahong Shi, State Key Laboratory of Estuarine and Coastal Research, East China Normal University, 3663 Zhongshan Road (N), Shanghai 200062, China e-mail: [email protected] Organotin compo...

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Persistent Toxic Substances

Annex 12 addresses definitions, general principles, programs, monitoring, early warning system, human health, research, and reporting. This annex embraces the philosophy of zero discharge and the goal of virtual elimination, and the Parties have achieved considerable success in controlling direct, point source discharges of toxic chemicals to the lakes. The Commission finds, however, that there...

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Environmental behavior of organotin compounds in the coastal environment of Xiamen, China.

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ژورنال

عنوان ژورنال: Japanese Journal of Zoo and Wildlife Medicine

سال: 2002

ISSN: 1342-6133,2185-744X

DOI: 10.5686/jjzwm.7.53